从病毒诱导细胞衰老看长新冠的中医病机演变

牛 梦茹, 邵宏 涛*
南京中医药大学附属中西医结合医院老年医学科

摘要


2019新型冠状病毒感染(COVID-19)至今仍在全球范围内持续蔓延,已成为对人类健康的重大威胁和全
球公共卫生问题。新型冠状病毒感染进入恢复期后,常会出现多个系统的症状,称之为新型冠状病毒感染后长期症
状,简称为“长新冠”(Long Covid)。近期研究发现细胞衰老,一种年龄相关的细胞状态,不仅是新冠急性期引起
高炎症反应的关键调节因子,也可能导致了长新冠的病机。而SARS-CoV-2可以通过多种机制诱发细胞衰老,即病
毒诱导衰老(VIS)。中医中药对COVID-19的诊治贯穿始终。在进入恢复期,尤其是长新冠的患者,中医对其辨治
论治更具有独特的优势。现将SARS-CoV-2诱导细胞衰老的机制及衰老相关因子对长新冠的影响和由此引起的中医
辨证论治进展作一综述。

关键词


长新冠综合征;细胞衰老;疫病;病机演变

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参考


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