经颅交流电刺激对视觉皮静息态的研究

孟 　佳, 武 文双, 华 春杰

摘要


经颅交流电刺激（transcranial Alternating Current Stimulation，tACS）是一种非侵入式、无痛的神经调控技术，
将周期性的交变弱电流作用于指定脑区，调节大脑皮层兴奋性，实现对大脑神经活动的调节。目前，稳态视觉诱发
电位（Steady-State Visual Evoked Potential，SSVEP）的研究受到视觉诱发易疲劳以及诱发频率少等问题的限制。采用
tACS神经调控技术，从大脑信号源的角度通过短时间提高大脑神经活动来增强脑电特征，从根本上提高SSVEP的信
号质量，为提高其性能提供理论依据。本文探究tACS对视觉皮层静息态的作用效应，将tACS电极置于枕区视觉皮
层，采用2mA的交流电刺激，先后采集刺激组和对照组的睁闭眼脑电数据，结果显示，tACS可提高alpha频段顶枕
区的睁闭眼脑电幅值，且睁眼相较于闭眼幅值升高的趋势更加明显，可知tACS可增强alpha频段的大脑活动。

关键词


经颅交流电刺激；静息态；视觉皮层

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