不同生物活性涂层对钛表面改性的研究进展

袁 　青, 章 可可
温州医科大学　口腔医学院

摘要


钛材料及其合金因其具有生物相容性和高耐腐蚀性，被广泛应用于口腔种植修复体、整形外科骨组织修复
替代材料等。但钛及其合金是惰性材料，植入后不能快速与骨组织结合，导致种植体周围形成骨性连接缓慢，从而
影响创伤处的骨重建速度；除此以外，种植体材料极易造成周围组织感染或细菌性炎症，导致口腔种植手术的成功
率降低。因此，对钛及其合金种植体表面进行生物修饰，以提高合金的抗菌能力和促进细胞分化成骨能力，一直是
生物材料领域的研究热点。本文就钛材料表面用酶、蛋白质及其核酸涂层进行生物改性的研究进展作一综述，以期
促进钛材料在口腔临床实践中的应用。

关键词


钛；酶涂层；生物涂层；生物修饰；表面改性

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参考


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DOI: http://dx.doi.org/10.12361/2661-3654-06-03-133199

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