人类温度适应遗传机制研究的回顾与展望

王迟 早*, 王 海燕
皖南医学院法医学院

摘要


“环境—基因—表型”之间复杂的相互作用不仅驱动着人类适应性进化的过程,对疾病机理也有着深远的影
响。伴随着测序技术的快速发展,人们不仅发现了一些环境适应的关键基因,也关注到了它们对于免疫、代谢等疾
病发生机制的影响。在众多环境影响因素中,湿热与寒冷是中国南北人群分别面对的核心自然选择压力之一。本文
对温度与环境适应的遗传机制研究进展、温度适应与某些疾病风险之间的可能联系以及目前研究中面临的主要挑战
等进行综述,并对未来的发展趋势作出展望,希望为相关研究提供参考。

关键词


温度;适应性进化;表型;基因

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参考


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