宏基因组二代测序与侵袭性肺真菌病

黄  祺, 李建 民*
湖南师范大学附属第一医院

摘要


侵袭性肺真菌病的发病率及病死率逐年上升,早期识别病原体对患者的早期诊断、治疗方案的指导、预后
有重大临床意义。本文对于三种常见侵袭性肺真菌病的特点进行了概述。传统检测的方法有检出率低、假阳性可能
等缺点,临床上对于新检测方法的需求不断上升。宏基因组二代测序有高通量、耗时短、无偏倚等优点,还可检出
未知病原体。综上,本文对传统检测法及宏基因组二代测序在背景、临床意义、优势、劣势方面进行了概括。

关键词


侵袭性肺真菌病;宏基因组二代测序;诊断

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参考


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