Trop2 CAR-T细胞疗法在肺腺癌治疗中的前景与挑战:从基础研究到临床转化

蔡 新培1, 徐 芹芹2, 郭 海梅3
1、青海大学
2、青海大学附属人民医院
3、青海大学医学院

摘要


本综述探讨了Trop2作为肺腺癌治疗的潜在靶点,并分析了Trop2 CAR-T细胞疗法的研究进展。尽管其在
体内外研究中展示出显著的抗肿瘤活性,但其临床应用仍面临脱靶效应、肿瘤微环境影响等挑战,本综述提出了可
能的解决策略,为该疗法的临床转化提供了指导,并期待其能在更多肿瘤治疗中展现出显著的疗效。

关键词


Trop2;肺腺癌;CAR-T

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