不可切除胰腺癌减黄治疗进展
摘要
胰腺癌的治疗仍然是一个挑战。这种癌症的五年生存率不超过10%。目前,胰腺癌的诊治方法有很多选择性,如外
科、化疗、放疗、分子靶向治疗、免疫学方法和综合治疗。其中,手术仍然是胰腺癌的主要治疗方法。不幸的是,
初次诊断出胰腺癌时有80%的患者已经失去手术机会。高达70%的胰腺癌患者伴随着黄疸,这严重影响了患者的姑
息性系统性治疗。本文综述了不可切除胰腺癌伴黄疸的减黄治疗方式。全面分析不可切除胰腺癌伴黄疸减黄治疗的
前景,旨在更深入地了解现有减黄方法,并尝试增强对不可切除胰腺癌患者伴黄疸的减黄治疗效果。
关键词
全文:
PDF参考
[1]国家卫生健康委办公厅.胰腺癌诊疗指南(2022
年版).临床肝胆病杂志,2022,38(5),1006-1030.
[2]孔冉.胰腺导管腺癌的定量蛋白质组学研究.博士
学位论文,军事科学院,2023. https://doi.org/10.27193/
d.cnki.gjsky.2022.000061.
[3]Wang, Y.; Wen, N.; Xiong, X.; Li, B.; Lu, J. Biliary
Drainage in Malignant Biliary Obstruction: An Umbrella
Review of Randomized Controlled Trials. Front Oncol 2023,
13, 1235490. https://doi.org/10.3389/fonc.2023.1235490.
[4]Duan, F.; Cui, L.; Bai, Y.; Li, X.; Yan, J.; Liu, X.
Comparison of Efficacy and Complications of Endoscopic
and Percutaneous Biliary Drainage in Malignant Obstructive
Jaundice: A Systematic Review and Meta-Analysis. Cancer
Imaging 2017, 17 (1), 27. https://doi.org/10.1186/s40644-
017-0129-1.
[5]Füldner, F.; Meyer, F.; Will, U. EUS-Guided
Biliary Interventions for Benign Diseases and Unsuccessful
ERCP - a Prospective Unicenter Feasibility Study on a Large
Consecutive Patient Cohort. Z Gastroenterol 2021, 59 (9),
933-943. https://doi.org/10.1055/a-1540-7975.
[6]Dumonceau, J.-M.; Vonlaufen, A. Pancreatic
Endoscopic Retrograde Cholangiopancreatography (ERCP).
Endoscopy 2007, 39 (2), 124-130. https://doi.org/10.1055/
s-2006-945096.
[7]Tempero, M. A.; Malafa, M. P.; Al-Hawary, M.;
Behrman, S. W.; Benson, A. B.; Cardin, D. B.; Chiorean,
E. G.; Chung, V.; Czito, B.; Del Chiaro, M.; Dillhoff, M.;
Donahue, T. R.; Dotan, E.; Ferrone, C. R.; Fountzilas,
C.; Hardacre, J.; Hawkins, W. G.; Klute, K.; Ko, A. H.;
Kunstman, J. W.; LoConte, N.; Lowy, A. M.; Moravek, C.;
Nakakura, E. K.; Narang, A. K.; Obando, J.; Polanco, P.
M.; Reddy, S.; Reyngold, M.; Scaife, C.; Shen, J.; Vollmer,
C.; Wolff, R. A.; Wolpin, B. M.; Lynn, B.; George, G.
V. Pancreatic Adenocarcinoma, Version 2.2021, NCCN
77
Advances in Mordern Medical
Clinical Practice Guidelines in Oncology. J Natl Compr
Canc Netw 2021, 19 (4), 439-457. https://doi.org/10.6004/
jnccn.2021.0017.
[8]Artifon, E. L. A.; Otoch, J. P.; Tchekmedyian, A. J.
A Review on Endoscopic Palliation of Obstructive Jaundice
before Surgery. Rev Gastroenterol Peru 2014, 34 (3), 225-
228.
[9]Sarkodie, B. D.; Botwe, B. O.; Brakohiapa, E.
K. K. Percutaneous Transhepatic Biliary Stent Placement
in the Palliative Management of Malignant Obstructive
Jaundice: Initial Experience in a Tertiary Center in Ghana.
Pan Afr Med J 2020, 37, 96. https://doi.org/10.11604/
pamj.2020.37.96.20050.
[10]Ma, J.; Luo, J.; Gu, J.; Liu, Q.; Liu, L.; Zhang, W.;
Zhang, Z.; Yan, Z. Malignant Obstructive Jaundice Treated
with Intraluminal Placement of Iodine-125 Seed Strands
and Metal Stents: An Analysis of Long-Term Outcomes and
Prognostic Features. Brachytherapy 2018, 17 (4), 689-695.
https://doi.org/10.1016/j.brachy.2018.04.001.
[11]Zhu, H.-D.; Guo, J.-H.; Huang, M.; Ji, J.-S.; Xu,
H.; Lu, J.; Li, H.-L.; Wang, W.-H.; Li, Y.-L.; Ni, C.-F.;
Shi, H.-B.; Xiao, E.-H.; Lv, W.-F.; Sun, J.-H.; Xu, K.;
Han, G.-H.; Du, L.-A.; Ren, W.-X.; Li, M.-Q.; Mao,
A.-W.; Xiang, H.; Zhang, K.-X.; Min, J.; Zhu, G.-Y.; Su,
C.; Chen, L.; Teng, G.-J. Irradiation Stents vs. Conventional
Metal Stents for Unresectable Malignant Biliary Obstruction:
A Multicenter Trial. J Hepatol 2018, 68 (5), 970-977.
https://doi.org/10.1016/j.jhep.2017.12.028.
[12]Canakis, A.; Baron, T. H. Relief of Biliary
Obstruction: Choosing between Endoscopic Ultrasound
and Endoscopic Retrograde Cholangiopancreatography.
BMJ Open Gastroenterol 2020, 7 (1), e000428. https://doi.
org/10.1136/bmjgast-2020-000428.
[13]Hara, K.; Yamao, K.; Mizuno, N.; Hijioka,
S.; Imaoka, H.; Tajika, M.; Tanaka, T.; Ishihara, M.;
Okuno, N.; Hieda, N.; Yoshida, T.; Niwa, Y. Endoscopic
Ultrasonography-Guided Biliary Drainage: Who, When,
Which, and How? World J Gastroenterol 2016, 22 (3), 1297-
1303. https://doi.org/10.3748/wjg.v22.i3.1297.
[14]Alvarez-Sánchez, M. V.; Luna, O. B.; Oria, I.;
Marchut, K.; Fumex, F.; Singier, G.; Salgado, A.; Napoléon,
B. Feasibility and Safety of Endoscopic Ultrasound-Guided
Biliary Drainage (EUS-BD) for Malignant Biliary Obstruction
Associated with Ascites: Results of a Pilot Study. J Gastrointest
Surg 2018, 22 (7), 1213-1220. https://doi.org/10.1007/
s11605-018-3731-z.
[15]Heger, U.; Hackert, T. Can Local Ablative
Techniques Replace Surgery for Locally Advanced Pancreatic
Cancer? J Gastrointest Oncol 2021, 12 (5), 2536-2546.
https://doi.org/10.21037/jgo-20-379.
[16]李茂全.晚期胰腺癌介入治疗临床操作指南(试
行)(第六版).临床肝胆病杂志,2022,38(6),1242-
1251.
[17]Jiang, J.; Lou, Q.; Yang, J.; Zhang, X. Feasibility
and Safety of EUS-Guided Radiofrequency Ablation in
Treatment of Locally Advanced, Unresectable Pancreatic
Cancer. Endosc Ultrasound 2021, 10 (5), 398-399. https://
doi.org/10.4103/EUS-D-21-00013.
[18]Yousaf, M. N.; Ehsan, H.; Muneeb, A.; Wahab,
A.; Sana, M. K.; Neupane, K.; Chaudhary, F. S. Role of
Radiofrequency Ablation in the Management of Unresectable
Pancreatic Cancer. Frontiers in Medicine 2021, 7, 624997.
https://doi.org/10.3389/fmed.2020.624997.
[19]S, S.; L, R.; D, F.; A, D.; M, C.; R, M.; R, I.
Irreversible Electroporation for the Management of Pancreatic
Cancer: Current Data and Future Directions. World journal
of gastroenterology 2023, 29 (2). https://doi.org/10.3748/
wjg.v29.i2.223.
[20]Wei, Y.; Xiao, Y.; Wang, Z.; Hu, X.; Chen, G.;
Ding, X.; Fan, Y.; Han, Y.; Huang, K.; Huang, X.; Kuang,
M.; Lang, X.; Li, H.; Li, C.; Li, J.; Li, J.; Li, M.; Lu, Y.;
Ni, C.; Niu, L.; Sun, J.; Tian, J.; Wang, H.; Wang, L.; Wu,
P.; Xie, X.; Xing, W.; Xu, L.; Yang, P.; Yu, H.; Yuan, C.;
Zhai, B.; Zhang, Y.; Zheng, J.; Zhou, Z.; Zhu, X.; Jiang,
T.; Zhang, Y. Chinese Expert Consensus of Image-Guided
Irreversible Electroporation for Pancreatic Cancer. J Cancer
Res Ther 2021, 17 (3), 613-618. https://doi.org/10.4103/
jcrt.JCRT_1663_20.
Refbacks
- 当前没有refback。