瑞马唑仑在老年患者全身麻醉中的研究进展
摘要
长时间应用不会蓄积,且对呼吸循环影响小等特点。由于其涉及组织酯酶的独特代谢途径,不会增加肝肾代谢负担,
是老年患者理想的麻醉药物之一。本文就近年来瑞马唑仑应用于老年患者全身麻醉的研究进行综述,为更广泛应用
于老年患者麻醉提供参考。
关键词
全文:
PDF参考
[1]李时鸿,邵叶波,周建军.国家区域医疗中心创
建老年友善医院实践探索[J].中国医院,2024,28(7):
102-104.
[2]Keam S J. Remimazolam: First approval[J]. Drugs,
2020, 80(6): 625-633.
[3]Schüttler J, Eisenried A, Lerch M, et al.
Pharmacokinetics and pharmacodynamics of remimazolam
(CNS 7056) after continuous infusion in healthy
male volunteers: Part I. Pharmacokinetics and clinical
pharmacodynamics[J]. Anesthesiology, 2020, 132(4): 636-651.
[4]Zhao M J, Hu H F, Li X L, et al. The safety and
efficacy between remimazolam and propofol in intravenous
anesthesia of endoscopy operation: A systematic review and
meta-analysis[J]. International Journal of Surgery (London,
England), 2023, 109(11): 3566-3577.
[5]Fechner J, El-Boghdadly K, Spahn D R, et al.
Anaesthetic efficacy and postinduction hypotension with
remimazolam compared with propofol: A multicentre
randomised controlled trial[J]. Anaesthesia, 2024, 79(4): 410-
422.
[6]Hirota K. Remimazolam: A new string to the TIVA
bow[J]. Journal of Anesthesia, 2023, 37(3): 335-339.
[ 7 ] E i s e n r i e d A , S c h ü t t l e r J , L e r c h M , e t
al. Pharmacokinetics and pharmacodynamics of
remimazolam (CNS 7056) after continuous infusion in
healthy male volunteers: Part II. Pharmacodynamics of
electroencephalogram effects[J]. Anesthesiology, 2020, 132(4):
652-666.
[8]Chen Y, Gong C, Liu F, et al. Toward modelinformed precision dosing for remimazolam: A population
pharmacokinetic-pharmacodynamic analysis[J].
Pharmaceutics, 2024, 16(9): 1122.
[9]Oh J, Park S Y, Lee S Y, et al. Determination of
the 95% effective dose of remimazolam to achieve loss of
consciousness during anesthesia induction in different age
groups[J]. Korean Journal of Anesthesiology, 2022, 75(6):
510-517.
[10]Chae D, Kim H C, Song Y, et al. Pharmacodynamic
analysis of intravenous bolus remimazolam for loss of
consciousness in patients undergoing general anaesthesia:
A randomised, prospective, double-blind study[J]. British
Journal of Anaesthesia, 2022, 129(1): 49-57.
[11]He M, Gong C, Chen Y, et al. Effect of
remimazolam vs. propofol on hemodynamics during
general anesthesia induction in elderly patients: Singlecenter, randomized controlled trial[J]. Journal of Biomedical
Research, 2023, 38(1): 66-75.
Refbacks
- 当前没有refback。