术前肝功能储备正常的肝癌患者肝切除术后肝功能衰竭的 危险因素研究分析
摘要
发生机制的了解仍然有限,所以肝切除术后肝衰竭的定义尚未统一。综述了术前肝功能储备、肝癌肝切除术后肝衰
竭的定义、危险因素、肝功能评估方法。分析表明应重视术前肝功能储备并充分评估,术中采取优化手术方式控制
出血,保留足够的功能性肝实质,使术后剩余肝体积能够充分代偿,术后转入肝病 ICU进行诊治预防,从而降低肝
癌肝切除术后肝衰竭的发生率,进一步改善患者预后,使患者收益最大化。
关键词
全文:
PDF参考
[1]WU DQ, GAO F, SUN DS, et al. Surgical treatment
of giant primary liver cancer[J]. Chin J Clin Hepatol, 2011,
27( 4) : 372 -374. ( in Chinese)
吴德全,高峰,孙东升,等.巨大肝癌的外科手术治
疗 [J].临床肝胆病杂志,2011,27(4):372-374.
[2]REN Z, XU Y, ZHU S. Indocyanine green retention
test avoiding liver failure after hepatectomy for hepatolithiasis[J].
Hepatogastroenterology, 2012,59( 115) : 782 -784.
[3]Liver Failure and Artificial Liver Group, Chinese,
Severe Liver Disease and Artificial Liver Group, Ch.
Guideline for diagnosis and treatment of liver failure[J]. Chin J
Clin Infect Dis, 2013, 5( 6) : 321 -327. ( in Chinese)
[4]董家鸿.肝细胞癌治疗理念与策略的转变.中华消
化外科杂志,2009,8(2):85-87.
[5]SchneiderPD.Preoperativeassessmentofliverfunction.
SurgClinNorthAm,2004,84(2):355-373.
[6]Rahbari NN, Garden OJ, Padbury R, Brooke_xfffe_Smith M, et al: Posthepatectomy liver failure: a definition and
grading by the International Study Group of Liver Surgery
(ISGLS). Sur-gery 2011; 149: 713-724.
[7]Eguchi H, Umeshita K, Sakon M, Nagano H, et al:
Presence of active hepatitis associated with liver cirrhosis is
a risk factor for mortal-ity caused by posthepatectomy liver
failure. Dig Dis Sci 2000; 45: 1383-1388.
[8]Van den Broek MA, Olde Damink SW, De-jong
CH, Lang H, Malagó M, Jalan R, Saner FH: Liver failure
after partial hepatic resec-tion: definition, pathophysiology,
risk fac-tors and treatment. Liver Int 2008; 28: 767-780.
[9]KamathPS, WiesnerRH, MalinchocM, et al. A model
to predict survival in patients with end stage liver disease.
Hepatology, 2001, 33(2): 464-470.
[10]Cucchetti A, Ercolani G, Vivarelli M, et al. Impact
of model for end stage liver disease (MELD) score on
153
现代医学前沿 | 第2卷/第11期
Advances in Mordern Medical
prognosis after hepatectomy for hepatocellular carcinoma on
cirrhosis. Liver Transpl, 2006, 12(6): 966-971.
[11]Cescon M, Cucchetti A, Grazi GL, et al. Indication
of the extent of hepatectomy for hepatocellular carcinoma on
cirrhosis by a simple algorithm based on preoperati vevariables.
ArchSurg, 2009, 144(1): 57-63.
[12]LOCK JF, MALINOWSKI M, SEEHOFER D, et
al. Function and volume recovery after partial hepatectomy:
influence of preoperative liver function, residual liver volume,
and obesity[J]. Langenbecks Arch Surg, 2012, 397( 8) : 1297
-1304.
[13]MASSIMINO KP, KOLBECK KJ, ENESTVEDT
CK, et al. Safety and efficacy of preoperative right portal vein
embolization in patients at risk for postoperative liver failure
following major right hepatectomy[J]. HPB (Oxford), 2012,
14( 1) : 14 -19.
[14 ]U r at aK, K aw a saki S, M at sunami H, et al.
Calculation of child and adult standard liver volume for liver
transplantation. Hepatology, 1995, 21(5): 1317-1321.
[15]Azoulay D, Castaing, D, Smail A, Adam R, Cailliez
V, et al: Resection of nonresectable liver metastases from
colorectal cancer after percutaneous portal vein embolization.
Ann Surg 2000; 231: 480-486.
[16 ]Azoulay D, Ca staing D, Kri s sat J, Smail A,
Hargreaves GM, Lemoine A, et al: Percuta-neous portal vein
embolization increases the feasibility and safety of major liver
resection for hepatocellular carcinoma in injured liver. Ann
Surg 2000; 232: 665-672.
[17]XU XZ, LIU JZ, LI ZF, et al. Influencing factors
for liver failure after hepatectomy for primary liver cancer[J].
Mod Instrum Med, 2017, 23 (4) : 31 -33. ( in Chinese)
许显志,刘进忠,李志锋,等.原发性肝癌肝切除
术后发生肝衰竭的影响因素分析 [J].现代仪器与医疗,
2017,23(4):31-33.
[18 ] L IU JH, ZHENG X L, ZHENG Z, et al.
Perioperative risk factors for liver failure after hepatectomy of
primary hepatic carcinoma[J]. Chin Gen Pract, 2013, 16 ( 6) :
2036 -2038. ( in Chinese)
柳己海,郑小林,郑直,等.原发性肝癌肝切除术
后患者发生肝衰竭的围术期危险因素分析 [J].中国全科医
学,2013,16(6):2036-2038.
[19]SU Y, GONG Z. Analysis of factors affecting post
-operative hepatic failure of hepatocellular carcinoma patients
with bile duct thrombi [J]. Pract J Cancer, 2014, 29( 2) : 233
-236. ( in Chinese)
苏瑛,龚昭.肝癌伴胆管癌栓患者术后发生肝衰竭的
影响因素研究 [J].实用癌症杂志,2014,29(2):233-236.
[20]SUN ZD, JIANG Y, ZHU F, et al. Clinical analysis
of hepatic failure after hepatectomy for liver cancer associated
with cirrhosis[J]. J Hepatobiliary Surg, 2010, 22( 6) : 463
-465. ( in Chinese)
孙振棣,江勇,朱峰,等.原发性肝癌合并肝硬化肝
切除术后肝衰竭的临床分析 [J].肝胆外科杂志,2010,22
(6):463-465.
Refbacks
- 当前没有refback。