内脏脂肪对胃癌免疫治疗的影响

李 席灵1, 马晓 明*2
1、青海大学研究生院
2、青海大学附属医院

摘要


内脏脂肪与胃癌的发生、进展和治疗效果有相关性,作为储存在腹腔内脏器官周围的脂肪组织。内脏脂肪
过高,对胃癌的发病和进展可能有促进作用,对根治胃癌术中和手术后的并发症,也会增加发病的机率。此外,内
脏脂肪会因子分泌和胰岛素抵抗等机制而影响胃癌的发展,从而引起局部慢性炎症,改变脂肪细胞。在免疫治疗方
面,内脏脂肪可能通过调节肿瘤微环境和免疫细胞浸润,影响胃癌患者对免疫治疗的反应。了解内脏脂肪与胃癌免
疫治疗的关系对个性化治疗和改善预后至关重要,本综述旨在探讨内脏脂肪与胃癌之间的关系,并分析其对胃癌免
疫治疗效果的影响,以期为未来的研究方向提供指导。

关键词


内脏脂肪;胃癌;免疫治疗

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