下肢外周动脉疾病发生的危险因素及防治进展

华 世铭1, 朱吉 海*2
1、青海大学研究生院
2、青海大学附属医院心脏血管外科

摘要


下肢外周动脉疾病(Peripheral Artery Disease,PAD)是由内皮细胞损伤,脂质异常,炎症反应等因素引起
的下肢动脉粥样斑块形成,血栓形成,进而发生狭窄甚至闭塞的,以间歇性跛行,静息痛为主要临床表现的外周动
脉缺血性疾病。本病多发生于中老年人群,患者常伴有的高血压病,高脂血症,糖尿病等全身基础性疾病及不良习
惯可能与下肢 PAD的发生具有相关性。尽早干预可降低下肢 PAD患者截肢甚至死亡的风险,减轻家庭及社会经济负
担。故本文对导致下肢 PAD的危险因素及防治措施进行综述。

关键词


下肢外周动脉疾病;雌激素;炎症;血小板;血脂异常;地中海饮食

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参考


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