原发性渗出性淋巴瘤1例并文献复习

卢 爱荣1, 黄 炳臣2
1、右江民族医学院研究生学院
2、右江民族医学院附属医院病理科

摘要


目的:探讨原发性渗出性淋巴瘤(primary effusion lymphoma,PEL)的临床病理学特征、诊断及鉴别诊断。
方法:复习1例PEL的临床病理资料,对胸水标本常规离心、涂片后,沉渣包埋制成细胞蜡块,结合免疫组织化学
染色明确诊断。结果:PEL细胞学主要以中心母细胞和B免疫母细胞为特征,可见爆米花样、RS样细胞。肿瘤细
胞CD20、CD79a、MUM-1、Bcl-6、PAX-5和HHV-8阳 性 表 达, 而CD3、CD10、Bcl-2、CK7、TTF-1、Syn和
Calretinin阴性。结论:PEL是大B细胞淋巴瘤的罕见亚型,病理诊断细胞学和免疫组化标记,应注意与恶性间皮瘤、
转移性腺癌和转移性黑色素瘤等鉴别。

关键词


淋巴瘤;细胞学;细胞块;诊断;鉴别

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参考


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