妊娠期睡眠障碍研究现状与妊娠高血压的关系
摘要
障碍是孕期常见的健康问题,包括失眠、睡眠呼吸暂停、昼夜节律紊乱及睡眠质量下降等。这些障碍的发生与妊
娠期的生理、激素及心理变化密切相关。研究表明,妊娠期睡眠障碍不仅影响孕妇的生活质量,还可能导致多种
不良妊娠结局,如胎儿发育迟缓、早产和妊娠高血压。尤其是睡眠呼吸暂停和长期失眠等问题与妊娠高血压的发生
存在显著相关性,其机制可能涉及交感神经系统激活、氧化应激增加及内皮功能损伤等方面。此外,妊娠高血压
(hypertensive disorders during pregnancy,HDP)反过来也会加重睡眠障碍,形成恶性循环。未来研究应进一步明确两
者的因果关系及潜在机制,为临床干预提供依据,以改善母婴健康结局。
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