妊娠期睡眠障碍研究现状与妊娠高血压的关系

游 嘉幸
广州医科大学

摘要


妊娠期独特的生理、心理及激素水平变化使得孕妇易遭受多种睡眠障碍或可能加重其症状,妊娠期睡眠
障碍是孕期常见的健康问题,包括失眠、睡眠呼吸暂停、昼夜节律紊乱及睡眠质量下降等。这些障碍的发生与妊
娠期的生理、激素及心理变化密切相关。研究表明,妊娠期睡眠障碍不仅影响孕妇的生活质量,还可能导致多种
不良妊娠结局,如胎儿发育迟缓、早产和妊娠高血压。尤其是睡眠呼吸暂停和长期失眠等问题与妊娠高血压的发生
存在显著相关性,其机制可能涉及交感神经系统激活、氧化应激增加及内皮功能损伤等方面。此外,妊娠高血压
(hypertensive disorders during pregnancy,HDP)反过来也会加重睡眠障碍,形成恶性循环。未来研究应进一步明确两
者的因果关系及潜在机制,为临床干预提供依据,以改善母婴健康结局。

关键词


妊娠;睡眠障碍;妊娠高血压;不良妊娠结局

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