谷草转氨酶与血小板在酒依赖患者中的应用

罗 番番, 张许 来*
安徽医科大学精神卫生与心理科学学院

摘要


目的：探讨酒精性肝病（ALD）对血小板计数（PLT）的影响，并分析谷草转氨酶（AST）水平在此关系中的调节作用，旨在为精神医学领域中ALD患者的早期诊断和个性化戒断治疗提供新的干预策略。方法：本研究纳入2023年度于阜阳市第三人民医院确诊的153名酒依赖患者。数据分析包括描述性统计、组间差异分析、多元线性回归分析和交互作用检验。结果：ALD组的PLT显著低于无ALD组，AST水平显著高于无ALD组。交互作用分析显示，在低AST水平情况下，ALD患者的PLT平均值比无ALD患者低，AST与ALD对PLT的影响存协同效应（交互作用P=0.023）。结论：ALD对PLT的影响显著受AST水平调节，联合评估AST和PLT的变化，有助于ALD患者的早期诊断和个性化治疗，优化酒精依赖的管理和戒断过程。

关键词


酒精性肝病；血小板计数；谷草转氨酶；酒精戒断；协同作用

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参考


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