过敏性紫癜发病机制的研究进展

王 雪纯1, 黄秋 芳*2
1、承德医学院;保定市第一中心医院
2、保定市第一中心医院

摘要


过敏性紫癜病因尚未完全明确，但与感染、遗传因素及药物密切相关。发病机制涉及中性粒细胞与淋巴细胞比值（Neutrophil to Lymphocyte Ratio，NLR）升高、血小板（Platelet，PLT）增多及平均血小板体积（MeanPlateletVolume，MPV）降低等炎症反应标志物异常，同时C-反应蛋白（C-reactive Protein，CRP）等急性期蛋白显著升高，表明全身性炎症反应在疾病发展中起核心作用。未来需进一步探索多因素交互作用及免疫炎症通路的分子机制。

关键词


过敏性紫癜；IgA血管炎；炎症反应；血小板活化

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参考


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