慢性阻塞性肺疾病合并冠心病的CT研究进展

李 林芝, 冯 英
四川省建筑医院放射科

摘要


慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）是一种常见的呼吸系统疾病，而冠心病（coronary artery disease，CAD）是COPD常见的合并症及主要死亡原因之一。临床发现，COPD与CAD之间有共同的危险因素和发病机制，但对COPD合并CAD患者的早期诊断尚未达成共识。随着影像学检查技术的发展，CT检查方式成为COPD和CAD早期诊断的重要手段，在COPD与冠心病的相关性研究中起着重要作用。本文就近年COPD合并CAD的危险因素、发病机制以及CT研究进展展开综述。

关键词


慢性阻塞性肺疾病（COPD）；冠心病（CAD）；CT；危险因素；发病机制

全文:

PDF


参考


[1]Diaz-Guzman, E., Mannino, D.M., Epidemiology and prevalence of chronic obstructive pulmonary disease[J]. Clinics in chest medicine, 2014, 35(1): 7-16.

[2]《中国心血管健康与疾病报告》2021（冠心病部分内容）[J].心肺血管病杂志，2023，42（12）：1191-1198.

[3]Daher, A., Dreher, M., The bidirectional relationship between chronic obstructive pulmonary disease and coronary artery disease[J]. Herz, 2020, 45(2): 110-117.

[4]赵伟豪，步睿，等.慢性阻塞性肺疾病与冠状动脉疾病之间的双向关系[J].心脏杂志，2021，33：92-94+100.

[5]王亚芬，旷湘楠，等.慢性阻塞性肺疾病合并心血管疾病的研究进展[J].医学研究生学报，2022，35：418-423.

[6]刘洪如，慢性阻塞性肺疾病合并冠心病患者载脂蛋白A-Ⅰ、A-Ⅱ和血清淀粉样蛋白A水平及意义，2023.

[7]Williams, M.C., Murchison, J.T., et al., Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality[J]. Thorax, 2014, 69(8): 718-23.

[8]Zhu, Z., Wang, X., et al., Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis[J]. Respiratory research, 2019, 20(1): 64.

[9]Ronit, A., Kristensen, T., et al., Validation of lung density indices by cardiac CT for quantification of lung emphysema[J]. International journal of chronic obstructive pulmonary disease, 2018, 13: 3321-3330.

[10]刘云飞，苏工，等.非心电控CT扫描对慢阻肺合并冠心病患者冠脉血管钙化的诊断价值及影响因素分析[J].中国CT和MRI杂志，2021，19：1-3+10.

[11]Detrano, R., Guerci, A.D., et al., Coronary calcium as a predictor of coronary events in four racial or ethnic groups[J]. The New England journal of medicine, 2008, 358(13): 1336-45.

[12]Romme, E.A., McAllister, D.A., et al., Associations between COPD related manifestations: a cross-sectional study[J]. Respiratory research, 2013, 14(1): 129.

[13]Jiménez-Gómez, M., de-Torres-Tajes, J.P., Association Between Coronary Calcium Detection on Chest Computed Tomography and Ischemic Cardiovascular Events and Mortality in Asymptomatic Chronic Obstructive Pulmonary Disease Patients. Systematic Review of the Literature[J]. Open respiratory archives, 2024, 6(4): 100357.

[14]曹俊涛，彭冠亮，等.冠状动脉钙化积分在慢性阻塞性肺病中的初步研究[J].中国医学计算机成像杂志，2019，25：242-245.

[15]Bhatt, S.P., Nath, H.P., et al., Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort[J]. Respiratory research, 2018, 19(1): 257.

[16]Kim, J.J., Kim, D.B., et al., Relationship between airflow obstruction and coronary atherosclerosis in asymptomatic individuals: evaluation by coronary CT angiography[J]. The international journal of cardiovascular imaging, 2018, 34(4): 641-648.

[17]Chandra, D., Gupta, A., et al., Airflow Limitation and Endothelial Dysfunction. Unrelated and Independent Predictors of Atherosclerosis[J]. American journal of respiratory and critical care medicine, 2016, 194(1): 38-47.

[18]刘琳，郑云峰，等.冠脉易损斑块与慢性阻塞性肺病相关性研究[J].中国医学计算机成像杂志，2022，28：255-258.

[19]季宇萌，秦会园，等.心外膜脂肪体积与冠状动脉血管病变严重程度评估及预后的相关性研究[J].南京医科大学学报（自然科学版），2023，43：1108-1114.

[20]Lan, Y., Ma, Q., et al., Epicardial adipose tissue in patients with chronic obstructive pulmonary disease: systematic review with meta analysis and trial sequential analysis[J]. BMC pulmonary medicine, 2023, 23(1): 241.

[21]Zagaceta, J., Zulueta, J.J., et al., Epicardial adipose tissue in patients with chronic obstructive pulmonary disease[J]. PloS one, 2013, 8(6): e65593.


Refbacks

  • 当前没有refback。