粒细胞集落刺激因子与卵泡黄素化未破裂综合征的研究新进展

崔 旭1, 张朝 晖*2
1、承德医学院
2、保定市第一中心医院

摘要


未破裂卵泡黄素化综合征（luteinized unruptured follicles syndrome，LUFS）是一种由于排卵紊乱所导致的疾病，主要表现为在卵泡未破裂的情况下，呈现出正常的排卵周期表现，在超声下可以见到未破裂的卵泡依次黄素化、萎缩。而粒细胞集落刺激因子（G-CSF）是一种驱动造血的内源性细胞因子，近年来被发现在女性生殖系统中广泛表达，并参与卵泡发育、排卵、胚胎移植及子宫内膜容受性调节等多个过程。本文旨在综述G-CSF与LUFS发生发展的潜在关联、可能的作用机制，为LUFS的诊断和治疗提供新的思路。

关键词


粒细胞集落刺激因子；未破裂卵泡黄素化综合征；排卵障碍；不孕症

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参考


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