小野寺指数对75岁及以上老年食管鳞癌患者生存预后的相关分析

孙 蕊, 魏 洁*
安徽医科大学附属滁州医院

摘要


目的：探究放疗前小野寺指数在75岁及以上老年食管鳞癌放射治疗患者生存预后的相关性。方法：收集安徽医科大学附属滁州医院肿瘤科在2020年1月至2025年1月期间48名75岁以上食管鳞癌放疗患者的临床数据。将患者依据小野寺指数计算值分为营养良好组与营养不良组。主要应用单/多因素Cox比例风险模型对影响食管癌患者整体生存期的预后因素进行单变量和多变量分析。结果：OPNI是75岁及以上老年食管鳞癌患者总生存期的独立影响因素，OPNI高分组患者的死亡风险较OPNI低分组降低70.9%（HR=0.291，95%CI：0.13-0.609，P=0.001）。结论：小野寺指数可作为一项评估患者营养状态的临床指标，对预测老年食管鳞癌的预后具有一定意义。

关键词


食管恶性肿瘤；食管鳞状细胞癌；小野寺指数；放射治疗；预后

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参考


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