氨基酸代谢在口腔鳞癌中的研究进展

谢 和蓁
深圳大学

摘要


口腔鳞状细胞癌是口腔及颌面部最常见的恶性肿瘤，发病率高且预后较差。代谢重编程是恶性肿瘤的核心
特征之一，其中氨基酸代谢异常在OSCC发生发展中发挥着重要作用。近年来，氨基酸代谢在OSCC中的关键作用
日益受到关注。本文综述了谷氨酰胺和甲硫氨酸为主的氨基酸在OSCC中的代谢改变，及对免疫细胞功能的调控作
用，并总结了靶向其代谢的临床应用进展，为OSCC的精准诊疗提供新的方向与思路。

关键词


口腔鳞状细胞癌；氨基酸代谢；谷氨酰胺；甲硫氨酸；靶向治疗

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