脑卒中合并衰弱的临床研究和管理进展
摘要
异性的衰弱评估工具选择、二者之间的关系论证以及脑卒中衰弱患者的干预管理等五个方面进行综述,以期为脑卒
中合并衰弱的识别评估和干预管理提供新思路,从而改善卒中患者不良预后,提高其生活质量。
关键词
全文:
PDF参考
[1]中国脑卒中防治指导规范 [M].2 版 . 人民卫生出
版社.
[2]Yang X, Liu Z, Nie D, et al. Association between
pre-stroke frailty and post-discharge destination in acute
stroke among chinese older adults[J]. Topics in Stroke
Rehabilitation, 2024: 1-11.
[3]Xue Q L. The frailty syndrome: definition and natural
history[J]. Clinics in Geriatric Medicine, 2011, 27(1): 1-15.
[4]庞媛月,曹童童,董雪.老年脑卒中患者衰弱相
关研究进展[J].老年医学研究,2024,5(1):56-61.
[5]Baker J, Rubens M, Appunni S, et al. Frailty among
stroke patients and its effects on hospital outcomes[J]. Journal
of Stroke and Cerebrovascular Diseases, 2024, 33(11): 108016.
[6]Vazquez S, Stadlan Z, Lapow J M, et al. Frailty
and outcomes in lacunar stroke[J]. Journal of Stroke and
Cerebrovascular Diseases: the Official Journal of National
Stroke Association, 2023, 32(2): 106942.
[7]赵怡迪,廖若彤,张小培,等.60岁及以上老年
脑卒中患者的衰弱现状:一项来自中国社区的横断面调
查(英文)[J].中西医结合护理(中英文),2023,9(7):
134-140.
[8]樊凡,杨翠,王庆松.老年缺血性脑卒中患者衰
弱状态与脑卒中后认知障碍的相关性研究[J].中华老年心
脑血管病杂志,2018,20(12):1253-1257.
[9]Huang Y N, Yan F H, Wang X Y, et al. Prevalence
and risk factors of frailty in stroke patients: a meta-analysis
and systematic review[J]. Journal of Nutrition, Health &
Aging, 2023, 27(2): 96-102.
[10]马玉婷,王小燕,窦丽.基于随机森林算法的老
年轻型缺血性脑卒中患者衰弱现状及风险模型构建[J].中
华老年心脑血管病杂志,2025,27(2):187-191.
[11]张鑫宇,张磊,隋汝波.基于Logistic回归和人
工神经网络构建老年脑卒中患者衰弱预测模型[J].军事护
理,2023,40(2):10-14,19.
[12]林卫,苏俐莉,余天智,等.老年缺血性脑卒中
后遗症患者衰弱状况调查及其危险因素分析[J].中华老年
心脑血管病杂志,2021,23(5):499-502.
[13]黄亚楠,王鑫钰,陈燕茹,等 . 脑卒中患者合
并衰弱的研究进展 [J]. 中国护理管理,2023,23(2):
282-286.
[14]Burton J K, Stewart J, Blair M, et al. Prevalence and
implications of frailty in acute stroke: systematic review &
meta-analysis[J]. Age and Ageing, 2022, 51(3): afac064.
[15]尚晓峰,张莹,李虹,等.老年急性缺血性脑卒
中患者衰弱与卒中后抑郁的相关性研究[J].中国全科医
学,2020,23(30):3834-3838.
[16]Noguchi M, Kubo H, Kanai M, et al. Relationship
between pre-stroke frailty status and short-term functional
outcome in older patients with acute stroke-a mediation
analysis[J]. Archives of Gerontology and Geriatrics, 2021, 94:
104370.
[17]施杨,顾志娥,王林.老年急性脑卒中患者衰弱
发生情况及其与神经功能结局的关系[J].实用心脑肺血管
病杂志,2023,31(11):12-15.
[18]Evans N R, Wall J, To B, et al. Clinical frailty
independently predicts early mortality after ischaemic stroke[J].
Age and Ageing, 2020, 49(4): 588-591.
[19]Joyce N, Atkinson T, Mc Guire K, et al. Frailty
and stroke thrombectomy outcomes-an observational cohort
study[J]. Age and Ageing, 2022, 51(2): afab260.
[20]Pinho J, Küppers C, Nikoubashman O, et al.
Frailty is an outcome predictor in patients with acute ischemic
65
医学理论研究 | 第3卷/第4期
Medical Theory Research
stroke receiving endovascular treatment[J]. Age and Ageing,
2021, 50(5): 1785-1791.
[21]Fried L P, Tangen C M, Walston J, et al. Frailty
in older adults: evidence for a phenotype[J]. The Journals
of Gerontology. Series A, Biological Sciences and Medical
Sciences, 2001, 56(3): M146-156.
[22]Rockwood K, Song X, MacKnight C, et al. A global
clinical measure of fitness and frailty in elderly people[J].
CMAJ: Canadian Medical Association Journal = Journal De
L’association Medicale Canadienne, 2005, 173(5): 489-495.
[23]Gobbens R J J, Luijkx K G, Wijnen-Sponselee
M T, et al. In search of an integral conceptual definition of
frailty: opinions of experts[J]. Journal of the American Medical
Directors Association, 2010, 11(5): 338-343.
[24]Bektas A, Schurman S H, Sen R, et al. Aging,
inflammation and the environment[J]. Experimental
Gerontology, 2018, 105: 10-18.
[25]Fried L P, Hadley E C, Walston J D, et al. From
bedside to bench: research agenda for frailty[J]. Science of Aging
Knowledge Environment: SAGE KE, 2005, 2005(31): pe24.
[26]王守琦,姜虹,徐皎,等.急性脑卒中患者衰弱
风险预测模型的构建及验证[J].重庆医学,2024,53(20):
3100-3107.
[27]廖若彤,陈蕊,罗旺辉,等.成年急性缺血性脑
卒中患者衰弱现状及影响因素分析[J].重庆医学,2022,
51(21):3644-3649.
[28]潘海燕,顾则娟,李方,等.基于老年综合评估
分析卒中恢复期老年患者认知衰弱发生及影响因素[J].医
学研究与战创伤救治,2024,37(4):406-410.
[29]周将,赵亮,宁爱丽,等.老年缺血性脑卒中后
遗症住院患者发生衰弱的状况及其危险因素[J].中国医药
科学,2024,14(20):119-122,164.
[30]薛荣,张开利,陈保云,等.中老年脑卒中患
者多维衰弱发展轨迹及其影响因素研究[J].护理学报,
2024,31(6):6-12.
[31]Rockwood K, Mitnitski A. Frailty in relation to the
accumulation of deficits[J]. Journals of Gerontology. Series A,
Biological Sciences and Medical Sciences, 2007, 62(7): 722-727.
[32]阳佳家,李凤,刘光维,等.脑卒中病人衰弱评
估的研究进展[J].护理研究,2023,37(21):3878-3885.
[33]Kanai M, Noguchi M, Kubo H, et al. Pre-stroke
frailty and stroke severity in elderly patients with acute stroke[J].
Journal of Stroke and Cerebrovascular Diseases: the Official
Journal of National Stroke Association, 2020, 29(12): 105346.
[34]李言洵,刘足云,王笑峰,等.虚弱综合征评价
体系在脑卒中患者管理中的应用[J].中华老年心脑血管病
杂志,2016,18(10):1118-1120.
[35]董又鸣.衰弱对缺血性卒中患者行神经介入治疗
预后影响的研究[D].广州:广州中医药大学,2023.
[36]傅国娟.急性脑梗死患者溶栓后衰弱状况与生活
质量的相关性分析[J].上海护理,2024,24(6):38-40.
[37]齐琲,张振香,王永利,等.老年脑卒中住院患
者吞咽体验与衰弱和营养状况的相关性[J].中国康复理论
与实践,2020,26(11):1269-1274.
[38]奚兴,郭桂芳,孙静.中文版Tilburg衰弱评估量
表的信效度研究[J].护理学报,2013,20(16):1-5.
[39]王根群,张利峰,罗义,等.社区老年脑卒中患
者衰弱现状及影响因素研究[J].重庆医学,2024,53(1):
28-32,37.
[40]夏晗月,曹倩,周丹丹.老年脑卒中患者衰弱现
状及影响因素分析[J].上海护理,2022,22(1):28-32.
[41]Palmer K, Vetrano D L, Padua L, et al. Frailty
syndromes in persons with cerebrovascular disease: a systematic
review and meta-analysis[J]. Frontiers in Neurology, 2019,
10: 1255.
[42]Veronese N, Sigeirsdottir K, Eiriksdottir G, et al.
Frailty and risk of cardiovascular diseases in older persons:
the age, gene/environment susceptibility-reykjavik study[J].
Rejuvenation Research, 2017, 20(6): 517-524.
[43]Sergi G, Veronese N, Fontana L, et al. Pre-frailty
and risk of cardiovascular disease in elderly men and women:
the pro.V.a. study[J]. Journal of the American College of
Cardiology, 2015, 65(10): 976-983.
[44]Shrauner W, Lord E M, Nguyen X M T, et al.
Frailty and cardiovascular mortality in more than 3 million US
veterans[J]. European Heart Journal, 2021, 43(8): 818-826.
[45]Renedo D, Acosta J N, Koo A B, et al. Higher
hospital frailty risk score is associated with increased risk of
stroke: observational and genetic analyses[J]. Stroke, 2023,
54(6): 1538-1547.
[46]Pilotto A, Brass C, Fassbender K, et al. Premorbid
frailty predicts short- and long-term outcomes of reperfusion
66
treatment in acute stroke[J]. Journal of Neurology, 2022,
269(6): 3338-3342.
[47]赵瑞雪,马雅军,李晓东,等.衰弱合并脑血管
病研究进展[J].中国现代神经疾病杂志,2021,21(1):
30-33.
[48]王娇,商临萍.社区老年人衰弱风险预测模型的
研究进展[J].护理研究,2022,36(9):1598-1600.
[49]奚兴,郭桂芳.社区老年人衰弱现状及其影响因
素研究[J].中国护理管理,2014,14(12):1315-1319.
[50]刘华雪,刘太芳,于文静,等.社区老年人衰弱
现状及对生活质量的作用路径分析[J].护理研究,2019,
33(21):3645-3649.
[51]刘淑婷,朱爱勇,杨燕.老年脑卒中患者合并衰
弱的干预研究进展[J].国际老年医学杂志,2025,46(2):
230-234.
[52]Imaoka Y, Kawano T, Hashiguchi A, et al. Modified
frailty index predicts postoperative outcomes of spontaneous
intracerebral hemorrhage[J]. Clinical Neurology and
Neurosurgery, 2018, 175: 137-143.
[53]Kim M G, Gandhi C, Azizkhanian I, et al. Frailty
and spontaneous intracerebral hemorrhage: does the modified
frailty index predict mortality?[J]. Clinical Neurology and
Neurosurgery, 2020, 194: 105816.
[54]Munthe-Kaas R, Aam S, Saltvedt I, et al. Is frailty
index a better predictor than pre-stroke modified rankin
scale for neurocognitive outcomes 3-months post-stroke?[J].
BMC Geriatrics, 2022, 22(1): 139.
[55]Seamon B A, Simpson K N. The Effect of Frailty
on Discharge Location for Medicare Beneficiaries After Acute
Stroke[J]. Archives of Physical Medicine and Rehabilitation,
2019, 100(7): 1317-1323.
[56]Shi K, Tian D C, Li Z G, 等 . Global brain
inflammation in stroke[J]. The Lancet. Neurology, 2019,
18(11): 1058-1066.
[57]蒋奕晨,沈沁,朱光跃,等.脑卒中病灶与吞咽
障碍严重程度的关联:回顾性队列研究[J].中国康复医学
杂志,2025,40(4):528-533.
[58]Winovich D T, Longstreth W T, Arnold A M, et al.
Factors associated with ischemic stroke survival and recovery
in older adults[J]. Stroke, 2017, 48(7): 1818-1826.
[59]封彩云,王静远,马琰华,等.基于赋能理论的
护理在老年脑卒中合并衰弱患者中的应用效果[J].中西医
结合护理(中英文),2023,9(11):21-24.
[60]付秀云,封彩云.衰弱人群规范化管理的最佳证
据在老年脑卒中病人中的应用研究[J].循证护理,2023,
9(24):4423-4428.
Refbacks
- 当前没有refback。
