实时荧光成像技术在腹腔镜直肠癌术中淋巴结清扫的应用研究

梁 浩, 燕 速*
青海大学附属医院胃肠肿瘤外科

摘要


在我国直肠癌的发病率与死亡率在恶性肿瘤谱中位居前列，2022年中国结直肠癌新发病例为51.71万，居
恶性肿瘤第二位，其中直肠癌占比约50%[1]。直肠癌的治疗手段仍是以手术为主的综合治疗为主流，随着外科器械和
腹腔镜技术的发展，以腹腔镜手术为代表的微创术式逐渐成为直肠癌根治术的主流术式。淋巴结（LN）转移是直肠
癌复发的主要原因之一，根据是否有淋巴结转移进行准确的结直肠癌分期能够指导治疗方案，而且淋巴结转移与患
者的生存时间密切相关。未被发现的转移淋巴结是其复发的重要因素。淋巴结清扫是降低结直肠癌复发的有效方法。
由于淋巴结体积偏小，且与周围组织的颜色相似，缺乏自身的特征性表现，因此从肿瘤标本中分拣出足够的淋巴结
并不容易。术中实时荧光成像技术为上述问题提供了可行性较高的解决方案。本文通过查阅相关文献资料和笔者团
队的临床实践经验，围绕该技术在腹腔镜直肠癌手术中的应用及研究现状进行综述，并就临床应用中存在的相关问
题进行探讨。

关键词


直肠癌；淋巴结清扫；吲哚菁绿；荧光成像技术

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参考


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