侵袭性NK细胞白血病1例并文献复习及未来展望

曹 淑雅, 万 秋霞, 陆 丽娜, 刘 贝贝, 王素 云*
深圳市龙华区中心医院血液内科

摘要


侵袭性NK细胞白血病（Aggressive natural killer-cell leukemia ANKL）是一种NK细胞恶性增殖性疾病，起病
急，常以发热、肝脾淋巴结肿大、黄疸起病，通常伴有弥散性血管内凝血、噬血细胞综合征及多脏器功能衰竭，绝
大多数患者伴有EB病毒（EBV）感染，治疗上对多种化疗方案反应不佳，早期死亡率极高，中位生存时间一般都小
于2个月[1]，且临床上ANKL极少见。故我们报道1例侵袭性NK细胞白血病合并噬血细胞综合征患者，旨在提高对
该病的认识，早期诊断，早期治疗。

关键词


侵袭性NK细胞白血病；噬血细胞综合征；诊断

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参考


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