宫颈高级别鳞状上皮内病变锥切术后 高危型HPV持续感染的研究进展

苟 亚楠1, 金 海红2, 陈 思思2, 陈 晴3
1、河北医科大学研究生学院
2、秦皇岛市第一医院妇科病区
3、河北北方学院

摘要


目的：对宫颈高级别鳞状上皮内病变行宫颈锥切术后高危型人乳头瘤病毒持续感染的现状进行综述，分析
其关键风险因素并探讨临床管理策略。方法：系统性检索与归纳国内外相关研究文献。结果：术后高危型人乳头瘤
病毒持续感染是导致患者病变残留、复发乃至进展为宫颈癌的核心风险预测指标。其主要风险因素可归纳为宿主因
素、病毒因素、手术相关因素以及术后干预措施四大方面。结论：临床管理应立足于多维度风险因素的全面评估，
推行基于风险分层的个体化随访方案，并积极倡导术后接种人乳头瘤病毒疫苗，此为降低复发风险的关键所在。

关键词


高级别鳞状上皮内病变；宫颈锥切术；人乳头瘤病毒；持续感染；术后管理

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参考


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