纳米银与银离子在口腔消毒及口腔治疗中的应用

何 定庚1, 陈 曦2, 王 志永2
1、湖南师范大学
2、湖南伟方生命科技有限公司

摘要


银离子与纳米银在口腔抗菌领域应用已久，银离子制剂氟化银二胺已成熟用于儿童及老年根面龋干预，可
阻滞活动性龋损进展；纳米银氟化物、纳米银含漱液、纳米晶银牙周敷料均完成人体临床试验，对根管内粪肠球菌
生物膜、牙周创面细菌、正畸菌斑具备抑制效果。现有证据分层明显：龋病、牙周敷料、含漱护理有人体数据支撑，
根管冲洗、牙科改性材料多停留在体外与动物实验。纳米银可作为口腔消毒补充手段，但受粒径、释放速率影响安
全性存在差异，暂无法完全替代次氯酸钠、氯己定等标准药剂，仍需标准化长期对照研究完善临床依据。

关键词


纳米银, 银离子, 口腔消毒, 口腔抑菌

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参考


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