半夏白术天麻汤加减治疗缺血性脑卒中研究进展

辛 宝梅, 张 强
介休市中医医院

摘要


缺血性脑卒中具有发病率高、致残率高、死亡率高的特点，严重威胁人类健康。半夏白术天麻汤出自《医
学心悟》，功擅化痰熄风、健脾祛湿，为治疗风痰上扰证的经典名方，近年来被广泛应用于缺血性脑卒中（尤其风痰
瘀阻、痰瘀互结证型）的中西医结合治疗。本文综述了半夏白术天麻汤加减治疗缺血性脑卒中的理论基础、临床研
究进展及作用机制。临床研究显示，半夏白术天麻汤加减联合西医常规治疗及针刺等中医特色疗法，可有效改善患
者神经功能缺损评分、促进日常生活能力恢复，且安全性良好；基础研究表明，其神经保护作用涉及抗炎、抗氧化
应激、抑制铁死亡、保护线粒体功能、促进神经发生及调节肠道菌群等多靶点、多通路机制，体现了中药复方整体
调节的优势。本文亦分析了现有研究在样本量、随机盲法实施及远期疗效评价等方面的不足，并就未来研究方向提
出展望，以期为半夏白术天麻汤在缺血性脑卒中综合防治中的临床应用及进一步研究提供参考。

关键词


半夏白术天麻汤, 缺血性脑卒中, 中风, 中西医结合

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参考


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