神经退行性疾病中抗衰老蛋白对小胶质细胞作用

杨 丰帆, 王 志梅, 赵 心悦, 高 玉娇, 金 梅花
大连大学医学院

摘要


随着人类寿命延长，神经退行性疾病发病率也逐渐增加，由此可见衰老是神经退行性疾病最重要的危险因素。故，抗
衰老蛋白与神经退行性疾病作用机制越来越受社会重视。在神经退行性疾病发展过程中，脑中常驻特异性巨噬细胞—小胶质细
胞在其中发挥了重要作用，而研究发现，抗衰老蛋白也参与了对小胶质细胞的调控。本篇综述尝试总结各神经退行性疾病中相
关抗衰老蛋白调控小胶质细胞方面的研究进展 , 以期为各种神经退行性疾病的治疗提供更多具有可行性的新方法。

关键词


神经退行性疾病 ；抗衰老蛋白 ；小胶质细胞 ；神经炎症

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参考


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