内镜下粪菌移植治疗顽固型功能性便秘患者的有效性及安全性

刘 希, 王 佳程, 李 鹏程, 尚 书
沈阳市第五人民医院 内镜诊疗中心

摘要


目的 ：本研究旨在评估内镜下粪菌移植（FMT）治疗顽固型功能性便秘患者的有效性和安全性。方法 ：本研究采用单
臂临床试验设计，比较患者治疗前后在临床缓解率、每周自发排便次数和多项临床量表评分方面的差异。结果 ：结果显示，治
疗有效率为 92%，无效率仅有 8%。患者每周的自发排便次数达到 3 次以上。此外，粪菌移植在改善便秘患者的生活质量、便秘
症状、焦虑和抑郁状态上也表现良好的效果。患者均未观察到不良事件。结论 ：内镜下 FMT 治疗顽固型功能性便秘是一种有效
且安全的治疗方法，能够改善患者的临床症状、生活质量和精神状况。

关键词


粪菌移植 ；顽固型功能性便秘 ；有效性 ；安全性

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