炎症小体在肿瘤转移中的作用研究进展

舒 浩明1, 刘 永仪1, 陈 倩1, 姚 元春2
1、吉首大学第一附属医院
2、吉首大学教务处

摘要


炎症小体在肿瘤转移过程中发挥了重要作用，其功能状态显著影响患者预后。肿瘤细胞通过炎症小体介导的复杂炎症反应网络快速适应宿主微环境,增强侵袭性和诱导免疫抑制，促进肿瘤转移。并且，靶向炎症小体的治疗策略显示出广阔的临床应用前景。近年来，大量研究探讨了炎症小体在肿瘤转移中的作用。本文概述了炎症小体在驱动肿瘤转移过程中的作用及其机制研究进展，为炎症小体作为肿瘤转移治疗靶点相关研究厘清思路。

关键词


炎症小体；肿瘤；转移

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参考


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