多聚脱氧核糖核苷酸在医疗美容中的最新应用

高 原1, 刘 畅2, 王 博文2
1、恒昱生物制药山东有限公司
2、烟台市烟台山医院

摘要


多聚脱氧核糖核苷酸(Polydeoxyribonucleotide, PDRN)是一种来源于鱼精蛋白的生物分子,在医疗美容领域近年来备受关注。本文综述了PDRN在医疗美容中的最新应用。首先介绍了PDRN的生物学特性和作用机制,重点阐述了其在伤口愈合、皮肤再生、抗衰老和脱发治疗等方面的作用。其次,对PDRN在面部填充、皮肤美白、皱纹改善、疤痕修复等美容治疗中的临床应用进行了详细阐述,并总结了其安全性和有效性。最后,探讨了PDRN在医疗美容领域的发展前景和可能的研究方向,为其进一步应用提供了展望。

关键词


多聚脱氧核糖核苷酸;伤口愈合;抗衰老;美容

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参考


[1]Rho NK, Han KH, Cho M, Kim HS: A survey on the cosmetic use of injectable polynucleotide: The pattern of practice among Korean Dermatologists. Journal of cosmetic dermatology 2024, 23(4):1243-1252.

[2]Khan A, Wang G, Zhou F, Gong L, Zhang J, Qi L, Cui H: Polydeoxyribonucleotide: A promising skin anti-aging agent. Chinese Journal of Plastic and Reconstructive Surgery 2022, 4(4):187-193.

[3]Squadrito F, Bitto A, Irrera N, Pizzino G, Pallio G, Minutoli L, Altavilla D: Pharmacological Activity and Clinical Use of PDRN. Frontiers in pharmacology 2017, 8:224.

[4]Lee KWA, Chan KWL, Lee A, Lee CH, Wan J, Wong S, Yi KH: Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness. International journal of molecular sciences 2024, 25(15).

[5]Yi KH, Winayanuwattikun W, Kim SY, Wan J, Vachatimanont V, Putri AI, Hidajat IJ, Yogya Y, Pamela R: Skin boosters: Definitions and varied classifications. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024, 30(3):e13627.

[6]Colangelo MT, Galli C, Guizzardi S: The effects of polydeoxyribonucleotide on wound healing and tissue regeneration: a systematic review of the literature. Regenerative medicine 2020.

[7]Lin MY, Lin CS, Hu S, Chung WH: Progress in the Use of Platelet-rich Plasma in Aesthetic and Medical Dermatology. The Journal of clinical and aesthetic dermatology 2020, 13(8):28-35.

[8]Yu M, Lee JY: Polydeoxyribonucleotide improves wound healing of fractional laser resurfacing in rat model. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology 2017, 19(1):43-48.


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