基于“虚气留滞”理论探讨论治癌症相关性疲劳

黄 玉洁, 左 佳倩, 任 雯沁, 舒 鹏
南京中医药大学附属医院肿瘤内科

摘要


癌症相关性疲劳是影响肿瘤患者生存质量的核心症状之一,现代医学对其病理机制的认识集中于慢性炎症与代谢紊乱,尤与肿瘤微环境密切相关。本研究以中医“虚气留滞”理论为基础,系统探讨癌症相关性疲劳的病因病机与治疗策略。通过理论分析与中西医视角融合,提出CRF的核心病机为脾、肺、肾三脏气虚为本,导致气、血、痰、瘀等病理产物“留滞”为标,这与现代医学中肿瘤微环境的慢性炎症状态具有内在一致性。在此基础上,研究确立了“健运中焦、补虚通滞”的治疗原则,并探讨其通过调节免疫、抑制炎症、改善代谢等途径发挥作用的可能性。本文不仅为中医辨治CRF提供了系统的理论框架,也为构建中西医结合防治肿瘤相关疲劳的新路径提供了整合性思路。

关键词


癌症相关性疲劳;虚气留滞;肿瘤微环境;补虚通滞;中西医结合

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参考


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