中医药治疗围绝经期综合征作用机制研究进展

王 馨宇1, 张 多加2
1、黑龙江中医药大学
2、黑龙江中医药大学第一附属医院

摘要


中医认为围绝经期综合征的发生与绝经前后的生理特点有密切关系。围绝经期综合征与肾密切相关，常累及心、肝、脾等脏腑。冲任二脉的衰少常易导致肾阴阳失衡而发病。分析近年来中医治疗围绝经期综合征的相关文献，根据不同证型分析其作用机制，以望为临床治疗围绝经期综合征提供新的方向和思路。

关键词


围绝经期；中医药疗法；作用机制；综述

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参考


[1]陈蓉.《中国绝经管理与绝经激素治疗指南2023版》解读[J].协和医学杂志,2023,14(03):514-519.

[2]Li RX, Ma M, Xiao XR, Xu Y, Chen XY, Li B. Perimenopausal syndrome and mood disorders in perimenopause: prevalence, severity, relationships, and risk factors. Medicine (Baltimore). 2016 Aug;95(32):e4466. doi: 10.1097/MD.0000000000004466. PMID: 27512863; PMCID: PMC4985318.

[3]Zhu Y, Wei J, Yang X, Zhu W, Zhang W. Investigation on prevalence and risk factors associated with genitourinary syndrome of menopause in middle-aged and older women in Beijing community: a cross sectional study. BMC Womens Health. 2022 Dec 30;22(1):558. doi: 10.1186/s12905-022-02099-w. PMID: 36585649; PMCID: PMC9801667.

[4]Gold EB, Colvin A, Avis N, Bromberger J, Greendale GA, Powell L, Sternfeld B, Matthews K. Longitudinal analysis of the association between vasomotor symptoms and race/ethnicity across the menopausal transition: study of women's health across the nation. Am J Public Health. 2006 Jul;96(7):1226-35. doi: 10.2105/AJPH.2005.066936. Epub 2006 May 30. PMID: 16735636; PMCID: PMC1483882.

[5]Carlson K, Nguyen H. Genitourinary Syndrome of Menopause. 2024 Oct 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 32644723.

[6]冯晓玲，张婷婷.中医妇科学[M].北京：中国中医药出版社，2021：130-133。

[7]王睿,吴睦霖,王伟,等.左归丸对围绝经期抑郁症模型小鼠行为学影响及神经保护机制研究[J].医学研究杂志,2020,49(02):135-139.

[8]廖泽绮,史婧儒,王雨荷,等.左归丸含药血清对Hedgehog-GLi通路关键因子mRNA表达及骨吸收功能的影响[J].中国骨质疏松杂志,2024,30(06):807-812.

[9]李帅.加味左归饮治疗围绝经期失眠肝肾阴虚证的临床观察[D].云南中医药大学,2022.DOI:10.27460/d.cnki.gyzyc.2022.000278.

[10]鲁莎,谭从娥,肖雪,等.右归丸对激素型肾阳虚证miRNA表达谱的影响及其靶基因功能分析[J].辽宁中医杂志,2024,51(05):184-187+223-224.DOI:10.131 92/j.issn.1000-1719.2024.05.049.

[11]Lei SS, Huang XW, Li LZ, Wang XP, Zhang Y, Li B, Shou D. Explorating the mechanism of Epimedii folium-Rhizoma drynariae herbal pair promoted bone defects healing through network pharmacology and experimental studies. J Ethnopharmacol. 2024 Jan 30;319(Pt 3):117329. doi: 10.1016/j.jep.2023.117329. Epub 2023 Oct 24. PMID: 37879510.

[12]卿红英.右归丸联合雷火灸治疗围绝经期综合征合并睡眠障碍效果分析[J].医药前沿,2024,14(13):105-107.

[13]王亮.隔药灸脐联合针刺华佗夹脊穴治疗围绝经期综合征(肾阴阳两虚型）的临床疗效观察[D].山东中医药大学,2023.DOI:10.27282/d.cnki.gsdzu.2023.000 215.


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